Augmentation of exposure therapy with D-cycloserin…[Arch Gen Psychiatry. 2006] - PubMed Result
Hofmann SG, Meuret AE, Smits JA, Simon NM, Pollack MH, Eisenmenger K, Shiekh M, Otto MW.
Department of Psychology and Center for Anxiety and Related Disorders, Boston University, Boston, MA 02215, USA.
CONTEXT: Social anxiety disorder (SAD) is common and Impairing. Although exposure therapy is one of the most effective forms of psychotherapy for SAD, many patients remain symptomatic. Fear reduction in exposure therapy is similar to extinction learning, and early clinical data with specific phobias suggest that the treatment effects of exposure therapy for this conditiion may be enhanced with d-cycloserine, an agonist at the glutamatergic N-methyl-d-aspartate receptor. OBJECTIVE: To determine whether short-term treatment with 50 mg of d-cycloserine enhances the efficacy of exposure therapy for SAD.
Source: Augmentation of exposure therapy with D-cycloserin…[Arch Gen Psychiatry. 2006] - PubMed Result
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